SFA Faculty Listing

Timothy Bowden, Aquaculture
Stephanie Burnett, Horticulture
Beth Calder, Food Science
Lily Calderwood, Horticulture
Mary Ellen Camire, Food Science
Robert Causey, Animal Science
Susan Erich, Plant and Soil Chemistry
Eric Gallandt, Weed Ecology
Charlene Gray, Horticulture
Jianjun (Jay) Hao, Plant Pathology
Mark Hutton, Vegetable Crops
Pauline Kamath, Animal Health
Dorothy Klimis-Zacas, Clinical Nutrition
Anne Lichtenwalner, Animal Science
Robson Machado, Food Science
Ellen Mallory, Sustainable Agriculture
David Marcinkowski, Animal Science
Jade McNamara, Human Nutrition
Eileen Molloy, Human Nutrition
Renae Moran, Pomology
Angela Myracle, Human Nutrition
Balu Nayak, Food Science
Tsutomu Ohno, Soil Chemistry
Brian Perkins, Food Science
Jennifer Perry, Food Microbiology
Bryan Peterson, Horticulture
Greg Porter, Crop Ecology
Juan Romero, Animal Nutrition
Denise Skonberg, Food Science
Susan Sullivan, Human Nutrition
Mona Therrien, Human Nutrition
Matthew Wallhead, Horticulture
James Weber, Animal Science
Adrienne White, Professor Emerita
David Yarborough, Horticulture
Kate Yerxa, Human Nutrition

Dorothy J. Klimis-Zacas

Professor of Clinical NutritionZacas

Degree: Ph. D. 1982, Pennsylvania State University
Phone: 207.581.3124
Email: dorothea@maine.edu
Location: 232 Hitchner Hall

Website: Klimis-Zacas Laboratory

Professional Interests: Nutritional Physiology and Biochemistry, Nutrition and Vascular Function and Metabolism, Berry bioactives and their role on chronic disease (Cardiovascular, Hypertension, Metabolic Syndrome)

Teaching: FSN 101 Introduction to Food and Nutrition, FSN 420 Medical Nutrition Therapy II, FSN 510 Trace Minerals, FSN 584 Lipids, Diet and Cardiovascular Disease

Research: Recent research in my laboratory targets the areas below, in an attempt to unravel mechanisms of bioactive compounds in berries in attenuating oxidative stress, endothelial dysfunction and inflammation, the cause of several chronic diseases.

VASCULAR NUTRITION-NUTRITIONAL PHYSIOLOGY.  Role and mechanism of action of functional foods and food bioactives on vasomotor function and aortic glycosaminoglycan structure and metabolism as related to Cardiovascular Disase, Hypertension, Obesity-induced inflammation and the Metabolic Syndrome  with the use of biosensors

NUTRITIONAL BIOCHEMISTRY-NUTRIGENOMICS.  Berry bioactives and their mechanism of action on systemic and local inflammation and gene expression related to the Metabolic Syndrome Role of anthocyanins and phenolics on cell migration, signaling, angiogenesis and vascular remodeling related to Cardiovascular Disease and Atherosclerosis.

CLINICAL NUTRITION.  Human interventions to study the role of food bioactives on Cardiovascular Disease, attenuation of oxidative stress, endothelial function, DNA protection and repair and alterations of gut microbiota.

Recent Publications:

Del Bo’, C.; Porrini, M.; Campolo, J.; Parolini, M.; Lanti, C.; Klimis-Zacas, D.; Riso, P. 2016. A single blueberry (Vaccinium corymbosum) portion does not affect markers of antioxidant defense and oxidative stress in healthy volunteers following cigarette smoking. Mutagenesis 31:215-214.

Vendrame, S.; Zhao, A.; Merrow, T. Klimis-Zacas, D. 2015. The effects of wild blueberry consumption on plasma markers and gene expression related to glucose metabolism in the obese Zucker rat. J. Med. Food. 18:619-624.

Taverniti, V.; Fracassetti, D.; Del Bo’, C.; Lanti, C.; Minuzzo, M.; Klimis-Zacas, D.; Riso, P.; Guglielmetti, S. 2014. Immunomodulatory effect of a wild blueberry anthocyanin-rich extract in human caco-2 intestinal cells. J. Agric. Food Chem. 62:8364-8351.

Vendrame, S; Kristo, A.S.; Schuschke, D.A.; Klimis-Zacas, D. 2014. Wild blueberry consumption affects aortic vascular function in the obese Zucker rat. Appl. Physiol. Nutr. Metab. 39:255-261.

Vendrame, S; Daugherty, A.; Kristo, A.S.; Klimis-Zacas, D. 2014. Wild blueberry (Vaccinium angustifolium)-enriched diet improves dyslipidaemia and modulates the expression of genes related to lipid metabolism in obese Zucker rats. Br. J. Nutr. 111:194-200.