The dominoes fall after long-term antibiotic exposure

B Zhai, RT Wheeler

Cell Host & Microbe 30 (7), 903-905

Pseudomonas Synergizes with Fluconazole against Candida during Treatment of Polymicrobial Infection

S Hattab, AM Dagher, RT Wheeler

Infection and Immunity 90 (4), e00626-21

2 2022
Wastewater surveillance for SARS-CoV-2 on college campuses: initial efforts, lessons learned, and research needs

S Harris-Lovett, KL Nelson, P Beamer, HN Bischel, A Bivins, A Bruder, …

International journal of environmental research and public health 18 (9), 4455

83 2021
IL-23 signaling prevents ferroptosis-driven renal immunopathology during candidiasis

N Millet, NV Solis, D Aquilar, MS Lionakis, RT Wheeler, N Jendzjowsky, …


It takes two to tango: How a dysregulation of the innate immunity, coupled with Candida virulence, triggers VVC onset

A Ardizzoni, RT Wheeler, E Pericolini

Frontiers in Microbiology, 1449

17 2021
Perinuclear anti-neutrophil cytoplasmic antibodies (pANCA) impair neutrophil candidacidal activity and are increased in the cellular fraction of vaginal samples from women with …

A Ardizzoni, A Sala, B Colombari, LB Giva, C Cermelli, S Peppoloni, …

Journal of Fungi 6 (4), 225

5 2020
Redundant Trojan horse and endothelial-circulatory mechanisms for host-mediated spread of Candida albicans yeast

AK Scherer, BA Blair, J Park, BG Seman, JB Kelley, RT Wheeler

PLoS pathogens 16 (8), e1008414

9 2020
Candidalysin activates innate epithelial immune responses via epidermal growth factor receptor

J Ho, X Yang, SA Nikou, N Kichik, A Donkin, NO Ponde, JP Richardson, …

Nature communications 10 (1), 1-12

77 2019
Intravital imaging reveals divergent cytokine and cellular immune responses to Candida albicans and Candida parapsilosis

LS Archambault, D Trzilova, S Gonia, C Gale, RT Wheeler

MBio 10 (3), e00266-19

16 2019
Microglia and amyloid precursor protein coordinate control of transient Candida cerebritis with memory deficits

Y Wu, S Du, JL Johnson, HY Tung, CT Landers, Y Liu, BG Seman, …

Nature communications 10 (1), 1-15

66 2019
Studies into B-glucan recognition in fish suggests a key role for the C-type lectin pathway

J Petit, EC Bailey, RT Wheeler, CAF de Oliveira, M Forlenza, G Wiegertjes

Fish and Shellfish Immunology 91, 434-434

41 2019
The zebrafish as a model host for invasive fungal infections

EE Rosowski, BP Knox, LS Archambault, A Huttenlocher, NP Keller, …

Journal of Fungi 4 (4), 136

45 2018
Yeast and filaments have specialized, independent activities in a zebrafish model of Candida albicans infection

BG Seman, JL Moore, AK Scherer, BA Blair, S Manandhar, JM Jones, …

Infection and immunity 86 (10), e00415-18

30 2018
Epitope unmasking in vulvovaginal candidiasis is associated with hyphal growth and neutrophilic infiltration

E Pericolini, S Perito, A Castagnoli, E Gabrielli, A Mencacci, E Blasi, …

PLoS One 13 (7), e0201436

19 2018
Glucose Homeostasis Is Important for Immune Cell Viability during Candida Challenge and Host Survival of Systemic Fungal Infection

TM Tucey, J Verma, PF Harrison, SL Snelgrove, TL Lo, AK Scherer, …

Cell metabolism 27 (5), 988-1006. e7

128 2018
Dynamic fungal cell wall architecture in stress adaptation and immune evasion

A Hopke, AJP Brown, RA Hall, RT Wheeler

Trends in microbiology 26 (4), 284-295

100 2018
Candida albicans and Pseudomonas aeruginosa interact to enhance virulence of mucosal infection in transparent zebrafish

AC Bergeron, BG Seman, JH Hammond, LS Archambault, DA Hogan, …

Infection and immunity 85 (11), e00475-17

64 2017
Control of mucosal candidiasis in the zebrafish swim bladder depends on neutrophils that block filament invasion and drive extracellular-trap production

RL Gratacap, AK Scherer, BG Seman, RT Wheeler

Infection and immunity 85 (9), e00276-17

30 2017
In vitro detection of neutrophil traps and post-attack cell wall changes in Candida hyphae

A Hopke, RT Wheeler

Bio-protocol 7 (7), e2213-e2213

8 2017
Candida parapsilosis Protects Premature Intestinal Epithelial Cells from Invasion and Damage by Candida albicans

S Gonia, L Archambault, M Shevik, M Altendahl, E Fellows, JM Bliss, …

Frontiers in pediatrics 5, 54

11 2017
Polyclonal anti-Candida antibody improves phagocytosis and overall outcome in zebrafish model of disseminated candidiasis

AC Bergeron, SE Barker, KM Brothers, BC Prasad, RT Wheeler

Developmental & Comparative Immunology 68, 69-78

9 2017
β-(1, 3)-glucan unmasking in some Candida albicans mutants correlates with increases in cell wall surface roughness and decreases in cell wall elasticity

S Hasim, DP Allison, ST Retterer, A Hopke, RT Wheeler, MJ Doktycz, …

Infection and immunity 85 (1), e00601-16

41 2017
Hsf1 and Hsp90 orchestrate temperature-dependent global transcriptional remodelling and chromatin architecture in Candida albicans

MD Leach, RA Farrer, K Tan, Z Miao, LA Walker, CA Cuomo, RT Wheeler, …

Nature communications 7 (1), 1-13

90 2016
Phenotypic Plasticity Regulates Candida albicans Interactions and Virulence in the Vertebrate Host

EM Mallick, AC Bergeron, SK Jones Jr, ZR Newman, KM Brothers, …

Frontiers in microbiology 7, 780

34 2016
Neutrophil attack triggers extracellular trap-dependent Candida cell wall remodeling and altered immune recognition

A Hopke, N Nicke, EE Hidu, G Degani, L Popolo, RT Wheeler

PLoS pathogens 12 (5), e1005644

96 2016
Candidalysin is a fungal peptide toxin critical for mucosal infection

DL Moyes, D Wilson, JP Richardson, S Mogavero, SX Tang, J Wernecke, …

Nature 532 (7597), 64-68

552 2016
A zebrafish larval model reveals early tissue-specific innate immune responses to Mucor circinelloides

K Voelz, RL Gratacap, RT Wheeler

Disease models & mechanisms 8 (11), 1375-1388

62 2015
Fungal pathogens: survival and replication within macrophages

AS Gilbert, RT Wheeler, RC May

Cold Spring Harbor perspectives in medicine 5 (7), a019661

77 2015
Modeling mucosal candidiasis in larval zebrafish by swimbladder injection

RL Gratacap, AC Bergeron, RT Wheeler

JoVE (Journal of Visualized Experiments), e52182

19 2014
Masking of β (1-3)-glucan in the cell wall of Candida albicans from detection by innate immune cells depends on phosphatidylserine

SE Davis, A Hopke, SC Minkin Jr, AE Montedonico, RT Wheeler, …

Infection and immunity 82 (10), 4405-4413

67 2014
Utilization of zebrafish for intravital study of eukaryotic pathogen–host interactions

RL Gratacap, RT Wheeler

Developmental & Comparative Immunology 46 (1), 108-115

41 2014
The complex roles of NADPH oxidases in fungal infection

D Hogan, RT Wheeler

Cellular microbiology 16 (8), 1156-1167

37 2014
CX3CR1-dependent renal macrophage survival promotes Candida control and host survival

MS Lionakis, M Swamydas, BG Fischer, TS Plantinga, MD Johnson, …

The Journal of clinical investigation 123 (12), 5035-5051

197 2013
NADPH Oxidase-Driven Phagocyte Recruitment Controls Candida albicans Filamentous Growth and Prevents Mortality

KM Brothers, RL Gratacap, SE Barker, ZR Newman, A Norum, …

PLoS pathogens 9 (10), e1003634

95 2013
Mucosal candidiasis elicits NF-κB activation, proinflammatory gene expression and localized neutrophilia in zebrafish

RL Gratacap, JF Rawls, RT Wheeler

Disease models & mechanisms 6 (5), 1260-1270

74 2013
Differential Adaptation of Candida albicans In Vivo Modulates Immune Recognition by Dectin-1

MJ Marakalala, S Vautier, J Potrykus, LA Walker, KM Shepardson, …

PLoS pathogens 9 (4), e1003315

188 2013
Correction: Differential Adaptation of In Vivo Modulates Immune Recognition by Dectin-1.

MJ Marakalala, S Vautier, J Potrykus, LA Walker, KM Shepardson, …

PLoS Pathogens

Candida albicans induces arginine biosynthetic genes in response to host-derived reactive oxygen species

C Jiménez-López, JR Collette, KM Brothers, KM Shepardson, RA Cramer, …

Eukaryotic Cell 12 (1), 91-100

64 2013
Non-invasive imaging of disseminated candidiasis in zebrafish larvae

KM Brothers, RT Wheeler

JoVE (Journal of Visualized Experiments), e4051

33 2012
Zebrafish: a see-through host and a fluorescent toolbox to probe host–pathogen interaction

DM Tobin, RC May, RT Wheeler

PLoS pathogens 8 (1), e1002349

108 2012
Live imaging of disseminated candidiasis in zebrafish reveals role of phagocyte oxidase in limiting filamentous growth

KM Brothers, ZR Newman, RT Wheeler

Eukaryotic cell 10 (7), 932-944

138 2011
Linking high-resolution metabolic flux phenotypes and transcriptional regulation in yeast modulated by the global regulator Gcn4p

JF Moxley, MC Jewett, MR Antoniewicz, SG Villas-Boas, H Alper, …

Proceedings of the National Academy of Sciences 106 (16), 6477-6482

187 2009
Dynamic, Morphotype-Specific Candida albicans β-Glucan Exposure during Infection and Drug Treatment

RT Wheeler, D Kombe, SD Agarwala, GR Fink

PLoS pathogens 4 (12), e1000227

305 2008
Drug Induced Exposure Of The Fungal Pro-Inflammatory Molecule Beta-Glucan

RT Wheeler, GR Fink

US Patent App. 12/048,559

2 2008
Regulation of progenitor cell proliferation and granulocyte function by microRNA-223

JB Johnnidis, MH Harris, RT Wheeler, S Stehling-Sun, MH Lam, O Kirak, …

Nature 451 (7182), 1125-1129

1337 2008
A drug-sensitive genetic network masks fungi from the immune system

RT Wheeler, GR Fink

PLoS pathogens 2 (4), e35

383 2006
Saccharomyces cerevisiae mutant with increased virulence

RT Wheeler, M Kupiec, P Magnelli, C Abeijon, GR Fink

Proceedings of the National Academy of Sciences 100 (5), 2766-2770

122 2003
Dynamic localization of bacterial signaling proteins controlling differentiation and cell cycle progression

RT Wheeler

Stanford University

Differential localization of two histidine kinases controlling bacterial cell differentiation

RT Wheeler, L Shapiro

Molecular cell 4 (5), 683-694

233 1999
Protein localization during the Caulobacter crescentus cell cycle

RT Wheeler, JW Gober, L Shapiro

Current opinion in microbiology 1 (6), 636-642

21 1998
Transcriptional analysis of the Caulobacter 4.5 S RNA ffs gene and the physiological basis of an ffs mutant with a ts phenotype

E Winzeler, R Wheeler, L Shapiro

Journal of molecular biology 272 (5), 665-676

9 1997
Bacterial chromosome segregation: is there a mitotic apparatus?

RT Wheeler, L Shapiro

Cell 88 (5), 577-579

60 1997