Emily Spaulding, Ph.D., The George Wojtech Endowed Chair in Neurobiology at MDIBL and a “pipeline junior faculty” in the COBRE grant team will present on June 23.
What drives neurodegenerative diseases like amyotrophic lateral sclerosis (ALS)?
Dr. Spaulding will discuss how her lab leverages the advantages of a transparent roundworm to better understand the contribution of disrupted cell organization to neurodegenerative conditions like ALS.
Want to learn more about the animal models that make this research possible?
Watch this reel on C. elegans!
Register now to join us Monday, June 23, 2025 at 5 p.m.
in Maren Auditorium (#4 on map) or via Zoom.
The Spaulding Lab uses the optically clear nematode, C. elegans, which contain 302 well-characterized neurons, all of which are visible in an intact, living animal. The researchers combine CRISPR/Cas9-genetic engineering of neurodegenerative disease-associated genes with super-resolution imaging of living, adult worms to understand how disrupted cell organization leads to neuronal dysfunction.
The Lab’s goal is to uncover new therapeutic targets to treat neurodegenerative disease.
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