UMaine Institute of Medicine

Wound healing and tissue repair are complex biological phenomena that are associated with degenerative diseases such as diabetes mellitus, ischemic disorders and atherosclerosis. We are exploring the role, molecular mechanisms and genomic effects of polyphenols (anthocyanins and phenolic acids) on endothelial cell migration and angiogenesis as it relates to the above diseases.

The Metabolic Syndrome is a cluster of metabolic disorders that affects about 23 percent of adults in the US. and increases risk for cardiovascular disease, diabetes, stroke and atherosclerosis. We are exploring the role and signaling pathways of bioactive compounds extracted from berries and berry-enriched diets on endothelial function, inflammation, lipid metabolism and gene expression […]