The Madelaine Lab is exploring the zebrafish’s self-healing powers

The Madelaine Lab is exploring the zebrafish’s self-healing powers. Can we apply them to humans?

image of zebrafish cell
Vascular (green) and perivascular (magenta) cells in the zebrafish eye.

Zebrafish have a superpower: the ability to regenerate damaged tissues—eyes included! Now, the research group of Romain Madelaine, Ph.D., is making groundbreaking explorations of these regenerative feats, work that could lead to new approaches to disorders such as macular degeneration, glaucoma and diabetic retinopathy.

“At a very basic level, we are trying to characterize the mechanisms of cellular regeneration,” Madelaine says. “How do we use comparative biology to make the regeneration of healthy tissue more available to humans?”

The Madelaine lab in summer 2024. From left to right: Jessica Drent, Romain Menard, Caroline Halluin, Romain Madelaine, Ph.D., Bidhi Diwedi, Anindita Neog, Pritha Das.
Not pictured: Aissette Baanannou, Ph.D.

Read the story here. And note that the Madelaine lab’s work on vision restoration is the subject of an upcoming MDI Science Café, on January 13. You can register to participate here.