The CompuMAINE lab is an image and signal processing, analysis, and modeling laboratory located at the University of Maine flagship campus. It was founded by Dr. Andre Khalil.

By developing and implementing novel signal processing & image analysis techniques, and computational modeling, CompuMAINE integrates mathematics, physics, artificial intelligence, machine learning, data mining, and computational engineering approaches to study a wide variety of applications. Focused research projects are centered on radiomics, a new field of medical study that aims to extract large amounts of quantitative features from medical images using data-characterization algorithms. Applications include Medicine (cancer, neuroscience, muscular dystrophy), Biophysics (neuro-development, cell nucleus architecture), Biomedical Engineering (artificial bone implants, protein modeling, astrobiology), Physics / Geophysics / Astrophysics (climate change,  surface science, solar physics, interstellar medium, cosmology), and Pure Mathematics (fractal structures in Pascal’s Triangle).