17. T. Cheewawisuttichai, M. Brichacek “Development of a multifunctional neoglycoside auxiliary for applications in glycomics research” Org. Biomol. Chem. 2021, 19, 6613-6617.

Tetrazine neoglycoside glycan auxiliary

16.  A. Numan, M. Brichacek “Asymmetric Synthesis of Stereogenic Phosphorus P(V) Centers Using Chiral Nucleophilic Catalysis” Molecules 2021, 26 (12), 3661.

Oxidative substitution of phosphonates with asymmetric catalysts

15. T. Cheewawisuttichai, R. D. Hurst,  M. Brichacek “Transformation of aldehydes into nitriles in an aqueous medium using O-phenylhydroxylamine as the nitrogen source” Carbohydate Res. 2021, 502, Epub 108282.

O Phenylhydroxylamine conversion of aldehyde to cyanohydrin

14. E. N. Patel, R. B. Arthur, A. D. Nicholas, E. W. Reinheimer, M. A. Omary,M. Brichacek*, H. H. Patterson* “Synthesis, structure and photophysical properties of a 2D network with gold dicyanide donors coordinated to aza[5]helicene viologen acceptors” Dalton Trans. 2019, 48, 10288-10297.

Aza5 helicene viologen
Aza5 helicene viologen

13. P. Thirawatananond, R. L. McPherson, J. Malhi, S. Nathan, M. J. Lambrecht, M. Brichacek, P. J. Hergenrother, A. K. L. Leung, S. B. Gabelli “Structural analyses of NudT16-ADP-ribose complexes direct rational design of mutants with improved processing of poly(ADP-ribosyl)ated proteins.” Sci. Rep. 2019, 9, 5940.

PDB of Nudt16 with ADP Ribose

12. M. J. Lambrecht*, M. Brichacek*, E. Barkauskaite, A. Ariza, I. Ahel, P. J. Hergenrother “Synthesis of Dimeric ADP-Ribose and its Structure with Human Poly(ADP-Ribose) Glycohydrolase” J. Am. Chem. Soc. 2015, 137, 3558. *Equal Contribution

Pub 12 J Am Chem Soc 2015

11. N. A. McGrath, M. Brichacek “Trifluoroperacetic Acid” Encyclopedia of Reagents for Organic Synthesis 2012, John Wiley & Sons Ltd.


10. F. Li, D. Calabrese, M. Brichacek, I. Lin, J. T. Njardarson “Efficient Synthesis of Thiopyrans Using a Sulfur-Enabled Anionic Cascade” Angew. Chem. Int. Ed. 2012, 51, 1938-1941.

Pub 10 Angew Chem Int Ed 2012

9. M. Brichacek, M. N. Villalobos, A. Plichta, J. T. Njardarson “Stereospecific Ring Expansion of Chiral Vinyl Aziridines” Org. Lett. 2011, 13, 1110-1113.

Pub 9 Org Lett 2011

8. N. A. McGrath, J. R. Binner, G. Markopoulos, M. Brichacek, J. T. Njardarson “An Efficient Oxidative Dearomatization-Radical Cyclization Approach to Symmetrically Substituted Bicyclic Guttiferone Natural Products” Chem. Commun. 2010, 47, 209-211.

Pub 8 Chem Commun 2010

7. N. A. McGrath, M. Brichacek, J. T. Njardarson “A Graphical Journey of Innovative Organic Architectures That Have Improved Our Lives” J. Chem. Ed. 2010, 87, 1348-1349.


Top 200 rand Name Drugs by Retail Dollars in 2008

6. M. Brichacek, L. A. Batory, N. A. McGrath, J. T. Njardarson “The Strategic Marriage of Method and Motif. Total Synthesis of Varitriol” Tetrahedron 2010, 66, 4832-4840.

Pub 6 Tetrahedron 2010

5. M. Brichacek, L. A. Batory, J. T. Njardarson “Stereoselective Ring Expansion of Vinyl Oxiranes. Mechanistic Insights and Natural Product Total Synthesis” Angew. Chem. Int. Ed. 2010, 49, 1648-1651.

Pub 5 Angew Chem Int Ed 2010

4. M. Brichacek, J. T. Njardarson “Creative approaches towards the synthesis of 2,5-dihydro- furans, thiophenes, and pyrroles. One method does not fit all!” Org. Biomol. Chem. 2009, 7, 1761-1770.

Pub 4 Org Biomol Chem 2009

3. N. A. McGrath, C. A. Lee, H. Araki, M. Brichacek, J. T. Njardarson “An Efficient Substrate-Controlled Approach Towards Hypoestoxide, a Member of a Family of Diterpenoid Natural Products with an Inside-Out [9.3.1] Bicyclic Core.” Angew. Chem, Int. Ed. 2008, 47, 9450-9453.

Pub 3 Angew Chem Int ed 2008

2. M. Brichacek, D. Lee, J. T. Njardarson “Lewis Acid Catalyzed [1,3]-Sigmatropic Rearrangement of Vinyl Aziridines” Org. Lett. 2008, 10, 5023-5026.

Pub 2 Org Lett 2008

1. M. P. Brichacek, R. M. Carlson “Dihydropyran as a Template for Lactone Synthesis” Synthetic Commun. 2007, 37, 3541-3549.