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Maginnis Lab


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Our laboratory studies the host-pathogen relationship between viruses and cells to better understand cellular and molecular mechanisms underlying the complexities of viral disease. In particular, we study the human JC polyomavirus, which infects the majority of the population and causes the fatal demyelinating disease progressive multifocal leukoencephalopathy in the brain of immunosuppressed individuals. Our goal is to understand the basic biology of the virus and JCPyV pathogenesis in order to develop novel treatment options, which are currently very limited.

The Maginnis laboratory is committed to excellence in biomedical research and educational training. We aim to provide a collegial, supportive atmosphere that promotes a passion for scientific curiosity and research excellence in an environment where scientific research is fun and rewarding. We emphasize the importance of asking key scientific questions with creative, open minds to provide meaningful contributions in the fields of molecular virology and viral pathogenesis.

Image Description: Virion


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Contact Information

Maginnis Lab
5735 Hitchner Hall Room 320
Orono, ME 04469-5735
Phone: 207.581.2800 | Fax: 207.581.2801
The University of Maine
Orono, Maine 04469
207.581.1110
A Member of the University of Maine System