Recent Publications from the Maginnis Lab:

  • Sandberg, A.L., Bond, A.C.S., Bennett, L.J., Craig, S.E., Kirkby, L.C., Kraemer, A.R., Kelly, K.G.,and Maginnis, M.S. + (2024). GPCR Inhibitors Have Antiviral Properties against JC Polyomavirus Infection. Viruses, 16(10): 1559. +, Corresponding author.
  • Bond, A.C.S., Crocker, M.A., Wilczek, M.P., DuShane, J.K., Sandberg, A.L., Bennett, L.J., Leclerc, N.R., and Maginnis, M.S. High-throughput drug screen identifies calcium and calmodulin inhibitors that reduce JCPyV infection. Antiviral Research, 222: 105817. +, Corresponding author.
  • Maginnis, M.S. + (2023). Beta-arrestin and G protein-coupled receptor kinases in viral entry: A graphical review. Cellular Signaling, 102: 110558. +, Corresponding author.
  •  Mehmood, K., Wilczek, M.P., DuShane, J.K., Parent, M.T., Mayberry, C.L., Wallace, J.N., Levasseur, F.L., Fong, T.M., Hess, S.T.+, and Maginnis, M.S. + (2022). Dynamics and Patterning of 5-Hydroxytryptamine 2 Subtype Receptors in Response to Ligand JC Polyomavirus. Viruses, 14(12), 2597. +, Corresponding author. [Selected as Highlight Paper].
  • Regan, D., Fong, C., Bond, A.C.S., Desjardins, C., Hardcastle, J., Hung, S.H., Holmes, A.P., Schiffman, J.D., Maginnis, M.S., and Howell, C. (2022). Improved Recovery of Captured Airborne Bacteria and Viruses with Liquid-coated Air Filters. ACS Applied Materials & Interfaces, 14(45):50543-50556.
  • Wilczek, M.P., Pike, A.C., Craig, S., Maginnis, M.S.+, and King, B.L. + (2022) Rearrangement in the Hypervariable Region of JC Polyomavirus Genomes Isolated from Patient Samples and Impact on Transcription Factor-Binding Sites and Disease Outcomes. IMJS, 23(10), 5699. +, Corresponding authors.
  • Wilczek, M.P., Armstrong, F.A., Mayberry, C.L., King, B.L. and Maginnis, M.S.  (2021). PI3K/AKT/mTOR Signaling Pathway is Required for JCPyV Infection in Primary Astrocytes. Cells, 10(11), 3218.
  • Wilczek, M.P., Armstrong, F.J., Geohegan, R.P., Mayberry, C.L., DuShane, J.K., King, B.L., and Maginnis, M.S. (2021). The MAPK/ERK Pathway and the Role of DUSP1 in JCPyV Infection of Primary Astrocytes. Viruses, 13:1834.
  • Mayberry, C.L., Bond, C.S., Wilczek, M.P., Mehmood, K., and Maginnis, M.S. (2021). Sending Mixed Signals: Polyomavirus Entry and Trafficking. Current Opinion in Virology, 47:95-105. [Invited review].
  • Mayberry, C.L., Wilczek, M.P., Fong, T.M., Nichols, S.L., and Maginnis, M.S.(2021). GRK2 Mediates b-arrestin Interactions with 5-HT2 Receptors for JC Polyomavirus Endocytosis. In press, Journal of Virology. [Spotlight Article].
  • Mayberry, C.L. and Maginnis, M.S. (2020). Taking the scenic route: polyomaviruses utilize multiple pathways to reach the same destination. Viruses; 12(10):1168. [Invited Review].
  • Wilczek, M.P., DuShane, J.K., Armstrong, F.J., and Maginnis, M.S. (2020). JC Polyomavirus Infection Reveals Delayed Progression of the Infectious Cycle in Normal Human Astrocytes. Journal of Virology, 94(5): e01331-19. [Cover Illustration].
  • DuShane, J.K., Mayberry, C.L., Wilczek, M.P., Nichols, S.L., and Maginnis, M.S. (2019). JCPyV-Induced MAPK Signaling Activates Transcription Factors during Infection. International Journal of Molecular Sciences, 20(19):4779.
  • DuShane, J.K. and Maginnis, M.S. (2019) DNA Virus Exploitation of the MAPK-ERK Cascade. International Journal of Molecular Sciences, 20(14):3427. [Invited Review].
  • Assetta, B., Morris-Love, J., Gee, G.V., Atkinson, A., O’Hara, B.A., Maginnis, M.S., Haley, S.A., and Atwood, W.J. (2019). Genetic and Functional Dissection of the Role of Individual 5-HT2 Receptors as Entry Receptors for JC Polyomavirus. Cell Reports, 27(7):1960-1966.e6.
  • DuShane, J.K., Wilczek, M.P., Crocker, M.A., Maginnis, M.S.+ (2019). High-Throughput Characterization of Viral and Cellular Protein Expression Patterns during JC Polyomavirus Infection. Frontiers in Microbiology, 10:783.
  • Curthoys, N.M., Mlodzianoski, M.J., Parent, M., Butler, M.B., Raut, P., Wallace, J., Lilieholm, J., Mehmood, K., Maginnis, M.S., Waters, H., Busse, B., Zimmerberg, J., and Hess ST. (2019). Influenza Hemagglutinin Modulates Phosphatidylinositol 4,5-Bisphosphate Membrane Clustering. Biophysical Journal, 116(5):893-909.
  • Mayberry, C.L., Soucy, A.N., Lajoie, C.R., DuShane, J.K., and Maginnis, M.S.+ (2019). JC Polyomavirus Entry by Clathrin-Mediated Endocytosis is Driven by β-arrestin. Journal of Virology, 93(8):e01948-18. [Spotlight Article].
  • Maginnis M.S. Virus-Receptor Interactions: The Key to Cellular Invasion. In press June 2018: Journal of Molecular Biology.
  • DuShane, J.K., Wilczek, M.P., Mayberry, C.L., and Maginnis, M.S.  (2018). ERK is a Critical Regulator of JCPyV Infection. Journal of Virology, 14;92(7): pii: e01529-17.
  • Mayberry, C.L., Nelson, C.D.S., and Maginnis, M.S. (2017) JC Polyomavirus Attachment and Entry: Potential Sites for PML Therapeutics. Current Clinical Microbiology Reports, 4(3):132-141. [Invited Review].