Maginnis Lab

Publications

2025:

• Obeng, B., Bennett, L.J., West, B.E., Wagner, D.J., Fleming, P.J., Tasker, M.N., Lorenger, M.K., Smith, D.R., Systuk, T., Plummer, S.M., Eom, J., Paine, M.D., Frangos, C.T., Wilczek, M.P., Shim, J.K., Maginnis, M.S., and Gosse, J.A. (2025) Antimicrobial Cetylpyridinium Chloride Suppresses Mast Cell Function by Targeting Tyrosine Phosphorylation of Syk Kinase. Journal of Immunotoxicology, 21(1):2443397.

2024:

• Pike, A.M.C., Amal, S., Maginnis, M.S., and Wilczek, M.P. (2024). Evaluating Neural Network Performance in Predicting Disease Status and Tissue Source of JC Polyomavirus from Patient Isolates Based on the Hypervariable Region of the Viral Genome. Viruses, 17(1), 12.
• Sandberg, A.L., Bond, A.C.S., Bennett, L.J., Craig, S.E., Kirkby, L.C., Kraemer, A.R., Kelly, K.G.,and Maginnis, M.S. (2024). GPCR Inhibitors Have Antiviral Properties against JC Polyomavirus Infection. Viruses, 16(10): 1559.
• Bond, A.C.S., Crocker, M.A., Wilczek, M.P., DuShane, J.K., Sandberg, A.L., Bennett, L.J., Leclerc, N.R., and Maginnis, M.S. (2024). High-throughput Drug Screen Identifies Calcium and Calmodulin Inhibitors that Reduce JCPyV Infection. Antiviral Research, 222: 105817.

2023:

•  Maginnis, M.S.  (2023). Beta-arrestin and G protein-coupled Receptor Kinases in Viral Entry: A graphical review. Cellular Signaling, 102: 110558.

2022:

• Mehmood, K., Wilczek, M.P., DuShane, J.K., Parent, M.T., Mayberry, C.L., Wallace, J.N., Levasseur, F.L., Fong, T.M., Hess, S.T., and Maginnis, M.S. (2022). Dynamics and Patterning of 5-Hydroxytryptamine 2 Subtype Receptors in Response to Ligand JC Polyomavirus. Viruses, 14(12), 2597. [Selected as Highlight Paper].
• Regan, D., Fong, C., Bond, A.C.S., Desjardins, C., Hardcastle, J., Hung, S.H., Holmes, A.P., Schiffman, J.D., Maginnis, M.S., and Howell, C. (2022). Improved Recovery of Captured Airborne Bacteria and Viruses with Liquid-coated Air Filters. ACS Applied Materials & Interfaces, 14(45):50543-50556.
• Wilczek, M.P., Pike, A.C., Craig, S., Maginnis, M.S.⁺, and King, B.L⁺. (2022) Rearrangement in the Hypervariable Region of JC Polyomavirus Genomes Isolated from Patient Samples and Impact on Transcription Factor-Binding Sites and Disease Outcomes. IMJS, 23(10), 5699. +, Co-corresponding authors.

2021:

• Wilczek, M.P., Armstrong, F.A., Mayberry, C.L., King, B.L. and Maginnis, M.S. (2021). PI3K/AKT/mTOR Signaling Pathway is Required for JCPyV Infection in Primary Astrocytes. Cells, 10(11), 3218. 
• Wilczek, M.P., Armstrong, F.J., Geohegan, R.P., Mayberry, C.L., DuShane, J.K., King, B.L., and Maginnis, M.S. (2021). The MAPK/ERK Pathway and the Role of DUSP1 in JCPyV Infection of Primary Astrocytes. Viruses, 13:1834.
• Mayberry, C.L., Bond, C.S., Wilczek, M.P., Mehmood, K., and Maginnis, M.S. (2021). Sending Mixed Signals: Polyomavirus Entry and Trafficking. Current Opinion in Virology, 47:95-105. [Invited review].
• Mayberry, C.L., Wilczek, M.P., Fong, T.M., Nichols, S.L., and Maginnis, M.S. (2021). GRK2 Mediates b-arrestin Interactions with 5-HT₂ Receptors for JC Polyomavirus Endocytosis.  Journal of Virology, 95(7): e02139-20. [Spotlight Article].

2020:

• Mayberry, C.L. and Maginnis, M.S. (2020). Taking the scenic route: polyomaviruses utilize multiple pathways to reach the same destination. Viruses; 12(10):1168. [Invited Review].
• Wilczek, M.P., DuShane, J.K., Armstrong, F.J., and Maginnis, M.S. (2020). JC Polyomavirus Infection Reveals Delayed Progression of the Infectious Cycle in Normal Human Astrocytes. Journal of Virology, 94(5): e01331-19. [Cover Illustration].

2019:

• DuShane, J.K., Mayberry, C.L., Wilczek, M.P., Nichols, S.L., and Maginnis, M.S. (2019). JCPyV-Induced MAPK Signaling Activates Transcription Factors during Infection. International Journal of Molecular Sciences, 20(19):4779.
• DuShane, J.K. and Maginnis, M.S. (2019) Human DNA Virus Exploitation of the MAPK-ERK Cascade. International Journal of Molecular Sciences, 20(14):3427. [Invited Review].
• Assetta, B., Morris-Love, J., Gee, G.V., Atkinson, A., O’Hara, B.A., Maginnis, M.S., Haley, S.A., and Atwood, W.J. (2019). Genetic and Functional Dissection of the Role of Individual 5-HT₂ Receptors as Entry Receptors for JC Polyomavirus. Cell Reports, 27(7):1960-1966.e6.
• DuShane, J.K., Wilczek, M.P., Crocker, M.A., Maginnis, M.S.⁺ (2019). High-Throughput Characterization of Viral and Cellular Protein Expression Patterns during JC Polyomavirus Infection. Frontiers in Microbiology, 10:783.
• Curthoys, N.M., Mlodzianoski, M.J., Parent, M., Butler, M.B., Raut, P., Wallace, J., Lilieholm, J., Mehmood, K., Maginnis, M.S., Waters, H., Busse, B., Zimmerberg, J., and Hess ST. (2019). Influenza Hemagglutinin Modulates Phosphatidylinositol 4,5-Bisphosphate Membrane Clustering. Biophysical Journal, 116(5):893-909.
• Mayberry, C.L., Soucy, A.N., Lajoie, C.R., DuShane, J.K., and Maginnis, M.S.⁺ (2019). JC Polyomavirus Entry by Clathrin-Mediated Endocytosis is Driven by β-arrestin. Journal of Virology, 93(8):e01948-18. [Spotlight Article].

2018:

• Maginnis M.S. Virus-Receptor Interactions: The Key to Cellular Invasion. In press June 2018: Journal of Molecular Biology.
• DuShane, J.K., Wilczek, M.P., Mayberry, C.L., and Maginnis, M.S.  (2018). ERK is a Critical Regulator of JCPyV Infection. Journal of Virology, 14;92(7): pii: e01529-17.

2017:

• Mayberry, C.L., Nelson, C.D.S., and Maginnis, M.S. (2017) JC Polyomavirus Attachment and Entry: Potential Sites for PML Therapeutics. Current Clinical Microbiology Reports, 4(3):132-141. [Invited Review].