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SUMMARY:MDI Science Cafe: What drives neurodegenerative diseases like amyotrophic lateral sclerosis (ALS)?
DESCRIPTION:Emily Spaulding\, Ph.D.\, The George Wojtech Endowed Chair in Neurobiology at MDIBL and a “pipeline junior faculty” in the COBRE grant team will present on June 23. \nWhat drives neurodegenerative diseases like amyotrophic lateral sclerosis (ALS)? \nDr. Spaulding will discuss how her lab leverages the advantages of a transparent roundworm to better understand the contribution of disrupted cell organization to neurodegenerative conditions like ALS. \nWant to learn more about the animal models that make this research possible?\nWatch this reel on C. elegans! \nRegister now to join us Monday\, June 23\, 2025 at 5 p.m.\nin Maren Auditorium (#4 on map) or via Zoom. \nThe Spaulding Lab uses the optically clear nematode\, C. elegans\, which contain 302 well-characterized neurons\, all of which are visible in an intact\, living animal. The researchers combine CRISPR/Cas9-genetic engineering of neurodegenerative disease-associated genes with super-resolution imaging of living\, adult worms to understand how disrupted cell organization leads to neuronal dysfunction. \nThe Lab’s goal is to uncover new therapeutic targets to treat neurodegenerative disease. \nThe MDI Science Café Series is brought to you by Cross Insurance \n 
URL:https://umaine.edu/medicine/event/mdi-science-cafe-what-drives-neurodegenerative-diseases-like-amyotrophic-lateral-sclerosis-als/
LOCATION:Virtual
CATEGORIES:COBRE,Research
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