{"id":8,"date":"2019-12-04T11:26:44","date_gmt":"2019-12-04T16:26:44","guid":{"rendered":"https:\/\/new.umaine.edu\/kinglab\/?page_id=8"},"modified":"2024-08-07T10:41:51","modified_gmt":"2024-08-07T14:41:51","slug":"home","status":"publish","type":"page","link":"https:\/\/umaine.edu\/kinglab\/","title":{"rendered":"Home"},"content":{"rendered":"<style>.kb-row-layout-id8_4bbc9c-2a > .kt-row-column-wrap{align-content:start;}:where(.kb-row-layout-id8_4bbc9c-2a > .kt-row-column-wrap) > .wp-block-kadence-column{justify-content:start;}.kb-row-layout-id8_4bbc9c-2a > .kt-row-column-wrap{column-gap:var(--global-kb-gap-md, 2rem);row-gap:var(--global-kb-gap-md, 2rem);padding-top:var(--global-kb-spacing-sm, 1.5rem);padding-bottom:var(--global-kb-spacing-sm, 1.5rem);grid-template-columns:minmax(0, 2fr) minmax(0, 1fr);}.kb-row-layout-id8_4bbc9c-2a > .kt-row-layout-overlay{opacity:0.30;}@media all and (max-width: 1024px){.kb-row-layout-id8_4bbc9c-2a > .kt-row-column-wrap{grid-template-columns:minmax(0, 2fr) minmax(0, 1fr);}}@media all and (max-width: 767px){.kb-row-layout-id8_4bbc9c-2a > .kt-row-column-wrap{grid-template-columns:minmax(0, 1fr);}}<\/style><div class=\"kb-row-layout-wrap kb-row-layout-id8_4bbc9c-2a alignnone wp-block-kadence-rowlayout\"><div class=\"kt-row-column-wrap kt-has-2-columns kt-row-layout-left-golden kt-tab-layout-inherit kt-mobile-layout-row kt-row-valign-top\">\n<style>.kadence-column8_40d791-97 > .kt-inside-inner-col,.kadence-column8_40d791-97 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column8_40d791-97 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column8_40d791-97 > .kt-inside-inner-col{flex-direction:column;}.kadence-column8_40d791-97 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column8_40d791-97 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column8_40d791-97{position:relative;}@media all and (max-width: 1024px){.kadence-column8_40d791-97 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column8_40d791-97 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column8_40d791-97\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading8_f0d2c6-19, .wp-block-kadence-advancedheading.kt-adv-heading8_f0d2c6-19[data-kb-block=\"kb-adv-heading8_f0d2c6-19\"]{font-style:normal;}.wp-block-kadence-advancedheading.kt-adv-heading8_f0d2c6-19 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading8_f0d2c6-19[data-kb-block=\"kb-adv-heading8_f0d2c6-19\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading8_f0d2c6-19 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading8_f0d2c6-19[data-kb-block=\"kb-adv-heading8_f0d2c6-19\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<h2 class=\"kt-adv-heading8_f0d2c6-19 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading8_f0d2c6-19\">Systems Biology<\/h2>\n\n\n\n<p>Many aspects of human health can be traced to the ability of cells to sense and respond to infection, injury or other environmental changes.&nbsp; Cells orchestrate these essential biological processes through complex networks of genes, proteins and metabolites.&nbsp; The focus of our laboratory is to utilize genomic, computational and experimental approaches to understand the mechanisms of stress responses.&nbsp; Increased understanding of how these networks normally function will inform the development of therapies that restore their function when needed.<\/p>\n\n\n\n<p>Within these networks, genes function together with multiple layers of genetic regulation that include both protein coding and non-coding genes.&nbsp; Network models provide a powerful framework to predict the regulatory roles of genes. &nbsp;Current projects involve using genome-level data to build and analyze these networks.&nbsp; A specific focus is on non-coding RNAs, including microRNAs and long non-coding RNAs, that have important regulatory roles in heath and disease.<\/p>\n<\/div><\/div>\n\n\n<style>.kadence-column8_be7c4d-d2 > .kt-inside-inner-col,.kadence-column8_be7c4d-d2 > .kt-inside-inner-col:before{border-top-left-radius:0px;border-top-right-radius:0px;border-bottom-right-radius:0px;border-bottom-left-radius:0px;}.kadence-column8_be7c4d-d2 > .kt-inside-inner-col{column-gap:var(--global-kb-gap-sm, 1rem);}.kadence-column8_be7c4d-d2 > .kt-inside-inner-col{flex-direction:column;}.kadence-column8_be7c4d-d2 > .kt-inside-inner-col > .aligncenter{width:100%;}.kadence-column8_be7c4d-d2 > .kt-inside-inner-col:before{opacity:0.3;}.kadence-column8_be7c4d-d2{position:relative;}@media all and (max-width: 1024px){.kadence-column8_be7c4d-d2 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}@media all and (max-width: 767px){.kadence-column8_be7c4d-d2 > .kt-inside-inner-col{flex-direction:column;justify-content:center;}}<\/style>\n<div class=\"wp-block-kadence-column kadence-column8_be7c4d-d2\"><div class=\"kt-inside-inner-col\"><style>.wp-block-kadence-advancedheading.kt-adv-heading8_831ecb-15, .wp-block-kadence-advancedheading.kt-adv-heading8_831ecb-15[data-kb-block=\"kb-adv-heading8_831ecb-15\"]{font-style:normal;}.wp-block-kadence-advancedheading.kt-adv-heading8_831ecb-15 mark.kt-highlight, .wp-block-kadence-advancedheading.kt-adv-heading8_831ecb-15[data-kb-block=\"kb-adv-heading8_831ecb-15\"] mark.kt-highlight{font-style:normal;color:#f76a0c;-webkit-box-decoration-break:clone;box-decoration-break:clone;padding-top:0px;padding-right:0px;padding-bottom:0px;padding-left:0px;}.wp-block-kadence-advancedheading.kt-adv-heading8_831ecb-15 img.kb-inline-image, .wp-block-kadence-advancedheading.kt-adv-heading8_831ecb-15[data-kb-block=\"kb-adv-heading8_831ecb-15\"] img.kb-inline-image{width:150px;vertical-align:baseline;}<\/style>\n<h3 class=\"kt-adv-heading8_831ecb-15 wp-block-kadence-advancedheading\" data-kb-block=\"kb-adv-heading8_831ecb-15\">Lab News<\/h3>\n\n\n\n<p><a href=\"https:\/\/cugr.umaine.edu\/2022\/11\/22\/2022-23-cugr-and-msgc-academic-year-undergraduate-fellowship-recipients-announced\/\">Sarah Foust and Mykayla Weinstein Awarded Research Fellowships<\/a> (Nov. 22, 2022)<\/p>\n\n\n\n<p><a href=\"https:\/\/umaine.edu\/news\/blog\/2022\/10\/25\/ben-kings-lab-makes-sense-of-genetic-data\/\">Ben King\u2019s lab makes sense of genetic data<\/a> (Oct. 25, 2022)<\/p>\n\n\n\n<p><a href=\"https:\/\/umaine.edu\/news\/blog\/2022\/10\/25\/brandy-soos-mentorship-and-research-go-hand-in-hand\/\">Brandy Soos: Mentorship and research go hand in hand<\/a> (Oct. 25, 2022)<\/p>\n\n\n\n<p><a href=\"https:\/\/umaine.edu\/news\/blog\/2022\/10\/25\/samuel-weafer-using-student-research-to-become-a-better-scientist\/\">Samuel Weafer: Using student research to become a better scientist<\/a> (Oct. 25, 2022)<\/p>\n\n\n\n<p><a href=\"https:\/\/umaine.edu\/news\/blog\/2022\/01\/11\/king-testifies-in-legislative-committee-hearing\/\">King testifies in legislative committee hearing<\/a> (Jan. 11, 2022)<\/p>\n\n\n\n<p><a href=\"https:\/\/umaine.edu\/news\/blog\/2020\/04\/06\/umaine-names-2020-valedictorian-and-salutatorian\/\">Grace Smith: UMaine names 2020 valedictorian and salutatorian<\/a> (Apr. 6, 2020)<\/p>\n\n\n\n<p><a href=\"https:\/\/umaine.edu\/news\/blog\/2019\/04\/30\/grace-smith-alan-baez-awarded-barry-goldwater-scholarships\/\">Grace Smith, Alan Baez awarded Barry Goldwater Scholarships<\/a> (Apr. 30, 2019)<\/p>\n<\/div><\/div>\n\n<\/div><\/div>","protected":false},"excerpt":{"rendered":"<p>Systems Biology Many aspects of human health can be traced to the ability of cells to sense and respond to infection, injury or other environmental changes.&nbsp; Cells orchestrate these essential biological processes through complex networks of genes, proteins and metabolites.&nbsp; The focus of our laboratory is to utilize genomic, computational and experimental approaches to understand [&hellip;]<\/p>\n","protected":false},"author":1691,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_kad_blocks_custom_css":"","_kad_blocks_head_custom_js":"","_kad_blocks_body_custom_js":"","_kad_blocks_footer_custom_js":"","_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"footnotes":""},"class_list":["post-8","page","type-page","status-publish","hentry"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Home - Benjamin King Laboratory<\/title>\n<meta name=\"description\" content=\"Utilizing genomic, computational and experimental approaches to understand the mechanisms of human disease.\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link 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