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Molecular & Biomedical Sciences

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Faculty - John Singer

Phone: (207) 581-2808
Email/web: Send an Email


Ph.D. University of Georgia

Research interests

Vibriosis, caused in the Northeast and worldwide by the marine bacterium Vibrio anguillarum, is the most pervasive killer of inhabitants of oceanic and estuarine environments, causing mortalities in animals as diverse as bivalves, finfish, and marine mammals.

Under conditions of commercial mariculture cumulative mortalities may reach 40%, and vibriosis has been cited as the major worldwide impediment to the successful commercial rearing of coldwater trout and salmon species. Using an integrated approach of DNA technology, microbial physiology and genetics, and immunological techniques, research in the laboratory is directed at constructing a recombinant Vibrio anguillarum vaccine for the simultaneous protection of salmonids against vibriosis and viral diseases such as infectious pancreatic necrosis.

A significant portion of the forest products industry in Maine is involved in the production of timber for use in building materials and furniture, dictating that the wood be kiln dried. A minimum of 4 x 1010 lbs of water vapor and organics are removed annually from nearly 30 billion board feet of wood dried in the United States alone. Kiln drying systems can be viewed as either venting evaporated moisture into the environment, or as condensing the evaporated moisture to recover heat energy, allowing the aqueous condensate to drain from the kiln and onto the ground. Biological effects of these uncharacterized wood drying condensates have not been examined. A second research focus in the laboratory is aimed at characterizing the in vitro and in vivo toxicological effects of condensates on life forms from bacteria to eukaryotic cells to mammals.


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Contact Information

Molecular & Biomedical Sciences
5735 Hitchner Hall
Orono, Maine 04469-5735
Phone: (207) 581-2810 | Fax: (207) 581-2801E-mail: Chair:
The University of Maine
Orono, Maine 04469
A Member of the University of Maine System