Drs Tim Bowden and Ian Bricknell of the Aquaculture Research Institute, UMaine have been awarded a new MTI seed grant for novel vaccine development.
Vaccines are a key method of controlling disease in finfish aquaculture. However, most fish vaccines consist of crude bacterial suspensions where the mechanisms of protection are not well understood. Recent research by the applicants has identified a novel group of proteins that are expressed by bacteria during the end stages of an infection. Vaccines that include these proteins were very protective against the fish pathogen Aeromonas salmonicida in small-scale laboratory trials.